LUF6000
CAS No. : 890087-21-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $396 | In-stock |
| 10mg | $594 | In-stock |
| 25mg | $940 | In-stock |
| 50mg | $1320 | In-stock |
| 100mg | $2112 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-13236 |
| M.Wt: | 411.33 |
| Formula: | C22H20Cl2N4 |
| Purity: | >98 % |
| Solubility: | DMSO : 14.29 mg/mL (ultrasonic) |
LUF6000 is an orally active allosteric modulator of the A3 adenosine receptor. LUF6000 has potent anti-inflammatory effect[1][2]. In Vitro: Modulatory effect of 10 μM LUF6000 on Cl-IB-MECA-induced [35S]GTPγS binding in assays with HEK 293 cell membranes expressing human, dog, rabbit, or mouse A3 adenosine receptors with EC50 ranging from 39 to 172 nM[1]. In Vivo: LUF6000 induces anti-inflammatory effect in 3 experimental animal models of rat adjuvant induced arthritis, monoiodoacetate induced osteoarthritis, and concanavalin A induced liver inflammation in mice[2].
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