DL-Menthol
CAS No. : 89-78-1
(Synonyms: Racementhol)
| Size | Price | Stock |
|---|---|---|
| 500mg | $25 | In-stock |
| 1g | $30 | In-stock |
| 5g | $50 | In-stock |
| 10 g | Get quote | |
| 50 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-Y1683 |
| M.Wt: | 156.27 |
| Formula: | C10H20O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 1 mg/mL (ultrasonic) |
DL-Menthol (Racementhol) is an orally active, GABAaR positive allosteric modulator and UDP-glucuronosyltransferase (UGT) inhibitor that can cross the blood-brain barrier. DL-Menthol binds to GABAAR and exhibits an allosteric activation effect, enhancing GABA-mediated chloride influx and inhibiting neuronal excitability. DL-Menthol can induce surgical anesthesia in fish and inhibit the metabolic detoxification of tobacco carcinogens by human liver and intestinal UGT enzymes, resulting in reduced NNAL-N-Gluc production[1][2][3].
In Vivo:DL-Menthol (0.2-3.0 mM; water administration; single; short-term treatment) induces surgical anesthesia in a dose-dependent manner in medaka (Oryzias latipes), goldfish (Carassius auratus) and zebrafish (Danio rerio) models. At high concentrations (3.0 mM), it first induces rapid movement and then turns to anesthesia. Pretreatment with a GABAaR antagonist can prolong the anesthetic latency[1].
0.5 mM DL-Menthol induces 100%, 90% and 100% surgical anesthesia in medaka, goldfish and zebrafish, respectively[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- DL-Menthol
- Cat. No.:
- HY-Y1683
- Quantity:
Your information is safe with us.