8-Hydroxy-2'-deoxyguanosine


CAS No. : 88847-89-6

(Synonyms: 8-Oxo-2-Deoxyguanosine)

88847-89-6
Price and Availability of CAS No. : 88847-89-6
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100mg $20 In-stock
250mg $31 In-stock
1g $74 In-stock
5g $276 In-stock
25g $966 Get quote
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Cat. No. : HY-W011540
M.Wt: 283.24
Formula: C10H13N5O5
Purity: >98 %
Solubility: DMSO : 155 mg/mL (ultrasonic)
Introduction of 88847-89-6 :

8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis. In Vitro: 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases. The biomarker 8-Hydroxy-2'-deoxyguanosine (8-OHdG) or 8-oxodG has been a pivotal marker for measuring the effect of endogenous oxidative damage to DNA and as a factor of initiation and promotion of carcinogenesis. The biomarker has been used to estimate the DNA damage in humans after exposure to cancer-causing agents, such as tobacco smoke, asbestos fibers, heavy metals, and polycyclic aromatic hydrocarbons[1].

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