| Size | Price | Stock |
|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-12797 |
| M.Wt: | 428.86 |
| Formula: | C23H21ClO6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
GF 15 is a potent inhibitor of centrosomal clustering in tumor cells. IC50 & Target: Centrosomal clustering[1] In Vitro: GF 15 leads to multipolar mitosis induction with an EC50 of 900 nM. GF 15 exhibits potent cytotoxicity in a concentration-dependent manner against a broad spectrum of tumor cell types including colon, cervix, glioblastoma, pancreas, leukemia, and myeloma-derived cell lines with IC50s of 1-5 μM[1]. In Vivo: Treatment of mouse xenograft models of human colon cancer and multiple myeloma with GF 15 results in tumor growth inhibition and significantly prolonged survival[1].
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