JNJ-28312141


CAS No. : 885692-52-4

885692-52-4
Price and Availability of CAS No. : 885692-52-4
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Cat. No. : HY-13496
M.Wt: 460.57
Formula: C26H32N6O2
Purity: >98 %
Solubility:
Introduction of 885692-52-4 :

JNJ-28312141 is an inhibitor for colony-stimulating factor-1 receptor (CSF-1R or FMS), with an IC50 of 0.69 nM. JNJ-28312141 inhibits proliferation of BDBM, MV-4-11, M-o7e, TF-1 with an IC50s of 2.6, 21, 41 and 150 nM, respectively. JNJ-28312141 exhibits anti-inflammatory activity in mouse arthritis model[1]. IC50 & Target:IC50: 0.69 nM (CSF-1R or FMS)

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