AMG-47a
CAS No. : 882663-88-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $190 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-18303 |
| M.Wt: | 535.56 |
| Formula: | C29H28F3N5O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 34 mg/mL |
AMG-47a is a potent and orally active lymphocyte-specific protein tyrosine kinase (Lck) inhibitor, with an IC50 of 0.2 nM. AMG-47a also inhibits VEGF2, p38α, Jak3 and MLR and IL-2 with IC50s of 1 nM, 3 nM, 72 nM, 30 nM and 21 nM, respectively. AMG-47a has anti-inflammatory activity[1]. IC50 & Target:IC50: 0.2 nM (Lck), 1 nM (VEGF2), 3 nM (p38α), 72 nM (Jak3), 30 nM (MLR), 21 nM (IL-2)[1]
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