EGFR/ErbB-2/ErbB-4 inhibitor-3


CAS No. : 881001-19-0

881001-19-0
Price and Availability of CAS No. : 881001-19-0
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5mg $355 In-stock
10mg $535 In-stock
25mg $1065 In-stock
50mg $1600 In-stock
100mg $2400 In-stock
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Cat. No. : HY-103440
M.Wt: 355.75
Formula: C17H11ClFN5O
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 881001-19-0 :

EGFR/ErbB-2/ErbB-4 inhibitor-3 (compound 29) is a potent tyrosine kinase inhibitor with IC50s of 0.3, 1.1, 0.5, 2.5, 24 nM for erbB1, erbB2, erbB4, EGF, HER, respectively[1]. EGFR/ErbB-2/ErbB-4 inhibitor-3 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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