Phrixotoxin 3
CAS No. : 880886-00-0
| Size | Price | Stock |
|---|---|---|
| 100μg | $807 | Get quote |
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| Cat. No. : | HY-P1218 |
| M.Wt: | 4059.72 |
| Formula: | C176H269N51O48S6 |
| Purity: | >98 % |
| Solubility: | H2O |
Phrixotoxin 3 is a potent blocker of voltage-gated sodium channels, with IC50s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively. Phrixotoxin 3 modulates voltage-gated sodium channels with properties similar to those of typical gating-modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current[1]. IC50 & Target:Sodium Channels[1]
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