SGB-1534 (hydrochloride)
CAS No. : 88068-72-8
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| Cat. No. : | HY-106418A |
| M.Wt: | 416.90 |
| Formula: | C21H25ClN4O3 |
| Purity: | >98 % |
| Solubility: |
SGB-1534 (hydrochloride) is an orally active, selective and competitive antagonist of the alpha 1-adrenoceptor and the 5-HT2 receptor. SGB-1534 (hydrochloride) can inhibit vasoconstriction and lower blood pressure. SGB-1534 (hydrochloride) can be used for the research of cardiovascular disease, such as hypertension[1][2].
In Vivo:SGB-1534 (hydrochloride) (0.1-3 mg/kg, p.o.) exhibits potent and long-lasting antihypertensive effects in conscious spontaneously hypertensive rats (SHRs), renal hypertensive rats and DOCA (HY-B1472)-salt rats, but it increased the heart rate only minimally[2].
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