CNT2 inhibitor-1
CAS No. : 880155-70-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $395 | In-stock |
| 10mg | $592 | In-stock |
| 25mg | $1066 | In-stock |
| 50mg | $1600 | In-stock |
| 100mg | $2400 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-112843 |
| M.Wt: | 448.47 |
| Formula: | C23H24N6O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 75 mg/mL (ultrasonic) |
CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2. IC50 & Target: IC50: 640 nM (hCNT2)[1][2]. In Vitro: CNT2 inhibitor-1 (compound 48) exhibits 81-fold more potent inhibitory activity than the parent compound 12. In addition, CNT2 inhibitor-1 exhibits inhibitory activity 1500-fold more potent than that of 2’-deoxy-5-fluorouridine, phlorizin, and 7,8,3’-trihydroxyflavone, which are well-known hCNT2 inhibitors[1]. CNT2 inhibitor-1 (compound 1) is a potent inhibitor with poor solubility[2].
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