Neuropathiazol


CAS No. : 880090-88-0

880090-88-0
Price and Availability of CAS No. : 880090-88-0
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5mg $153 In-stock
10mg $230 In-stock
25mg $468 In-stock
50mg $680 In-stock
100mg $988 In-stock
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Cat. No. : HY-10591
M.Wt: 338.42
Formula: C19H18N2O2S
Purity: >98 %
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Introduction of 880090-88-0 :

Neuropathiazol, a neuronal differentiation inducer, selectively induces neuronal differentiation of multipotent hippocampal neural progenitor cells[1]. In Vitro: Neuropathiazol (5-15 μM; 5 hours) significantly slows cell proliferation without visible cytotoxic effects[1].
Neuropathiazol (10 μM; 1-4 days) down-regulates Sox2 (a neural progenitor marker) and up-regulates NeuroD1 (a neuronal cell marker)[1].
Neuropathiazol also inhibits astroglial differentiation that is induced by LIF and BMP2[1].
Neuropathiazol induces neuronal differentiation of multipotent adult hippocampal neural progenitor cells[1].
Neuropathiazol can competitively suppress astrogliogenesis by LIF/BMP2/FBS in a dose-dependent manner[1].

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