Aurora kinase inhibitor-3


CAS No. : 879127-16-9

879127-16-9
Price and Availability of CAS No. : 879127-16-9
Size Price Stock
1mg $80 In-stock
5mg $200 In-stock
10mg $320 In-stock
25mg $565 In-stock
50mg $808 In-stock
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Cat. No. : HY-112373
M.Wt: 413.40
Formula: C21H18F3N5O
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 879127-16-9 :

Aurora kinase inhibitor-3 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50 of >10 μM. Aurora kinase inhibitor-3 has a binding mode with the cyclopropanecarboxylic acid moiety directed towards the solvent exposed region of the ATP-binding pocket[1].

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