Avarofloxacin


CAS No. : 878592-87-1

(Synonyms: JNJ-Q2)

878592-87-1
Price and Availability of CAS No. : 878592-87-1
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10mg $450 In-stock
25mg $940 In-stock
50mg $1500 In-stock
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Cat. No. : HY-16764
M.Wt: 419.42
Formula: C21H23F2N3O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic;adjust pH to 2 with HCl)
Introduction of 878592-87-1 :

Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial agent being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia with oral activity. Avarofloxacin (JNJ-Q2) is an aminoethylidenylpiperidine fluoroquinolone that demonstrates antibacterial effect against numerous Gram-positive bacteria with a mean 0.12 mg/L MIC90 value. Avarofloxacin (JNJ-Q2) has potential for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections[1][2][3]. In Vitro:Avarofloxacin exhibits high antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA), with a 90% minimum inhibitory concentration (MIC90) of 0.25 µg/mL[1].
Avarofloxacin has a MIC90 of 0.015 µg/mL against Streptococcus pyogenes, Streptococcus agalactiae and Streptococci[1].
Avarofloxacin has a MIC90 of 0.12 µg/mL against Streptococcus pneumoniae[1].
Avarofloxacin has a MIC90 of 0.015 µg/mL against Haemophilus influenzae[1].

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