JNJ 303
CAS No. : 878489-28-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $121 | In-stock |
| 10mg | $198 | In-stock |
| 25mg | $462 | In-stock |
| 50mg | $825 | In-stock |
| 100mg | $1210 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-16953 |
| M.Wt: | 440.98 |
| Formula: | C21H29ClN2O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 62.5 mg/mL (ultrasonic) |
JNJ-303 is a specific delayed rectifier Kv blocker. JNJ 303 can potent block IKs with an IC50 value of 64 nM. JNJ-303 can be used for the research of diabetes, obesity and central nervous system[1][2].
IC50 & Target:IC50: 64 nM (IKs)[1]
In Vitro:JNJ 303 can block IKs with an IC50 value of 64 nM[1].
JNJ 303 (3.3 μM) does not have any effects on other cardiac channels[1].
JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP)[1].
In Vivo:JNJ 303 recapitulates the Exn4-induced decrease in fasting blood glucose level in mice[2].
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