IPI-269609


CAS No. : 878204-96-7

878204-96-7
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Cat. No. : HY-13654
M.Wt: 423.63
Formula: C28H41NO2
Purity: >98 %
Solubility:
Introduction of 878204-96-7 :

IPI-269609 is an orally effective Smoothed (SMO) inhibitor that targets the Hedgehog (Hh) signaling pathway. IPI-269609 specifically reduces the ALDH-bright (high aldehyde dehydrogenase activity) cell subset, which is considered the "cancer stem cells" in pancreatic cancer. IPI-269609 significantly inhibits the migration and colony formation of pancreatic cancer cells. IPI-269609 effectively inhibits pancreatic cancer metastasis in a mouse model. IPI-269609 can be used for pancreatic cancer research[1].

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