GPBAR-A
CAS No. : 877052-79-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $560 | Get quote |
| 10mg | $896 | Get quote |
| 50mg | $2688 | Get quote |
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| Cat. No. : | HY-107612 |
| M.Wt: | 484.37 |
| Formula: | C23H15F7N2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
GPBAR-A is a specific agonist of the bile acid receptor GPBAR1. GPBAR-A can be used for the research of diabetes mellitus[1].
In Vitro:GPBAR-A (3 μM; 24-36 h) stimulates the release of glucagon-like peptide (GLP-1) in GLUTag cells[1].
GPBAR-A (3 μM; 24-36 h) increases GLP-1 release 4.2-fold in primary colonic cultures[1].
GPBAR-A (3 μM; 24-36 h) increases GLP-1 release 2.6-fold in upper small intestinal cultures[1].
GPBAR-A (3 μM; 24-36 h) also increases the cAMP concentration in GLUTag cells by 57%[1].
GPBAR-A (3 μM; 24-36 h) increases GLP-1 secretion in the presence of diazoxide (KATP channel opener, 340 μM) and 70 mM KCl[1].
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