6-Hydroxyrubiadin
CAS No. : 87686-86-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $210 | In-stock |
| 5mg | $530 | In-stock |
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| Cat. No. : | HY-N2714 |
| M.Wt: | 270.24 |
| Formula: | C15H10O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases[1].
In Vitro: 6-hydroxyrubiadin suppresses lipopolysaccharide (LPS)-induced nuclear factor-kappa B activation as well as the phosphorylation of c-Jun N-terminal kinase in RAW 264.7 macrophages[1].
6-hydroxyrubiadin inhibited the expression of tumor necrosis factor (TNF)-a, interleukin (IL)-1b and IL-6 in phorbol myristate acetate (PMA)-primed U937 and RAW 264.7cells[1].
In Vivo: 6-hydroxyrubiadin can reduce the production of pro-inflammatory cytokines and ameliorate acute lung injury (ALI) in a mouse model[1].
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