Octyl-α-ketoglutarate


CAS No. : 876150-14-0

(Synonyms: 1-Octyl 2-oxopentanedioate)

876150-14-0
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Cat. No. : HY-114333
M.Wt: 258.31
Formula: C13H22O5
Purity: >98 %
Solubility:
Introduction of 876150-14-0 :

Octyl-α-ketoglutarate (1-Octyl 2-oxopentanedioate) is a stable, cell-permeable form of α-ketoglutarate which accumulates rapidly in HEK293 cells with a dysfunctional tricarboxylic acid (TCA) cycle, stimulating prolyl hydroxylase (PHD) activity. In addition, Octyl-α-ketoglutarate competitively blocks succinate- or fumarate-mediated inhibition of PHD[1].

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