Fidaxomicin
CAS No. : 873857-62-6
(Synonyms: OPT-80; PAR-101)
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $65 | In-stock |
| 50mg | $90 | In-stock |
| 100mg | $150 | In-stock |
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| Cat. No. : | HY-17580 |
| M.Wt: | 1058.04 |
| Formula: | C52H74Cl2O18 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 33 mg/mL |
Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12?μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research[1][2][3].
In Vitro: Fidaxomicin selectively eradicates pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora[1].
Fidaxomicin is not inhibitory to commonly cultured bowel commensals (MIC90 >1024?μg/mL)[2].
In Vivo: Fidaxomicin (0-5 mg/kg, Orally, once a day for 5 days) completely prevents the lethality of the animals and prevents the occurrence of relapses in a hamster model for pseudomembranous colitis[3].
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