NVP-QAV680
CAS No. : 872365-16-7
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| Cat. No. : | HY-12284 |
| M.Wt: | 358.41 |
| Formula: | C18H18N2O4S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
NVP-QAV680 is a potent and selective CRTh2 receptor antagonist with low nanomolar (nM) functional potency to inhibit CRTh2-driven activation of human eosinophils and Th2 lymphocytes. NVP-QAV680 exhibits good oral bioavailability and demonstrates efficacy in CRTh2-dependent mechanisms and allergic disease models in rats[1][2].
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