AZD1092
CAS No. : 871656-65-4
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| Cat. No. : | HY-121070 |
| M.Wt: | 450.49 |
| Formula: | C24H26N4O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
AZD1092 is an orally active glucokinase (GK) activator with an EC50 value of 0.03 μM. AZD1092 can be used for the research of Type 2 Diabetes (T2D)[1].
IC50 & Target:EC50: 0.03 μM (glucokinase)[1]
In Vitro:AZD1092 has activity for glucokinase with an EC50 value of 0.03 μM[1].
In Vivo:AZD1092 (oral; 1, 3, 10 mg/kg) exhibits dose dependent reduction of glucose excursion and has glucose lowering efficacy in Zucker rats[1].
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