AC-262536


CAS No. : 870888-46-3

870888-46-3
Price and Availability of CAS No. : 870888-46-3
Size Price Stock
5mg $70 In-stock
10mg $98 In-stock
25mg $215 In-stock
50mg $350 In-stock
100mg $560 In-stock
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Cat. No. : HY-122025
M.Wt: 278.35
Formula: C18H18N2O
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 870888-46-3 :

AC-262536 is a selective and non-steroidal androgen receptor modulators (SARMs) with beneficial anabolic effects. AC-262536 exhibits potent agonist activity at the androgen receptor, with an affinity in the low nanomolar range (1-10 nM)[1]. In Vitro: AC-262536 dose-dependently inhibits dihydroxytestosterone (DHT)-induced proliferation of LNCaP. The effects are significant with 100 nM AC-262536 (%inhibition 47.2±12.2), and reaches a plateau with 1 μM treatment (%inhibition 50.7±7.6). Thus, AC-262536 can act as a functional antagonist in prostate cells[1]. In Vivo: AC-262536 (3, 10, 30 mg/kg) reverses the luteinizing hormone (LH) spike in castrated rats[1].

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