AMG-Tie2-1


CAS No. : 870223-96-4

870223-96-4
Price and Availability of CAS No. : 870223-96-4
Size Price Stock
1mg $55 In-stock
5mg $220 In-stock
10mg $380 In-stock
25mg $760 In-stock
50mg $1220 In-stock
100mg $1950 In-stock
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Cat. No. : HY-13023
M.Wt: 479.45
Formula: C25H20F3N5O2
Purity: >98 %
Solubility: DMSO : 175 mg/mL (ultrasonic)
Introduction of 870223-96-4 :

AMG-Tie2-1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) with an IC50 of 1 nM. AMG-Tie2-1 is a VEGFR2 inhibitor with an IC50 of 3 nM[1]. In Vitro: AMG-Tie2-1 (compound 15) inhibits Tie-2 phosphorylation in EA.hy926 human endothelial cells (IC50=10 nM).

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