Tozadenant
CAS No. : 870070-55-6
(Synonyms: SYN115)
| Size | Price | Stock |
|---|---|---|
| 5mg | $40 | In-stock |
| 10mg | $65 | In-stock |
| 25mg | $115 | In-stock |
| 50mg | $195 | In-stock |
| 100mg | $330 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-10995 |
| M.Wt: | 406.50 |
| Formula: | C19H26N4O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Tozadenant is an adenosine A2A receptor antagonist, with Ki of 11.5 nM on human A2A and 6 nM on rhesus A2A. IC50 & Target: Ki: 6 nM (Rhesus A2A), 11.5 nM (Human A2A) In Vivo: 18F-MNI-444 regional uptake is consistent with A2A receptor distribution in the brain. Selectivity is demonstrated by dose-dependent blocking by tozadenant (1.5, 10.5 mg/kg) and preladenant[1].
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