6-Chloropurine


CAS No. : 87-42-3

(Synonyms: 6-Chloro-9H-purine)

87-42-3
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Cat. No. : HY-Y0247
M.Wt: 154.56
Formula: C5H3ClN4
Purity: >98 %
Solubility: DMSO : 27.5 mg/mL (ultrasonic);H2O : 2.5 mg/mL (ultrasonic)
Introduction of 87-42-3 :

6-Chloropurine is a building block in chemical synthesis. Intermediate in the preparation of 9-alkylpurines and 6-rnercaptopurine. Antitumor activities[1]. In Vivo: 6-Chloropurine to S-(6-punnyl)glutathione and further metabolism of S-(6-punnyl)glutathione to 6-mercaptopunne may be involved in the mechanism of the 6-Chloropurine-induced antitumor activity[1]. 6-chloropurine and azaserine have been shown to have synergic antitumor properties in a variety of mouse neoplasms when administered simultaneously[1].

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