Isosorbide dinitrate
CAS No. : 87-33-2
(Synonyms: ISDN)
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| Cat. No. : | HY-B1409 |
| M.Wt: | 236.14 |
| Formula: | C6H8N2O8 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Isosorbide dinitrate (ISDN) is an NO donor that prevents LV remodeling and degradation of cardiac function following myocardial infarction (MI)[1].
In Vivo: Isosorbide dinitrate (3 mg/kg; intratracheal; for 13 days) improves pulmonary artery pressure and ventricular remodeling in a rat model of heart failure following myocardial infarction[1].
Isosorbide dinitrate postconditioning exhibits a cardioprotective effect against rat myocardial ischemia-reperfusion injury in vivo[2].
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