TLQP-21
CAS No. : 869988-94-3
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| Cat. No. : | HY-P1345 |
| M.Wt: | 2432.75 |
| Formula: | C107H170N40O26 |
| Purity: | >98 % |
| Solubility: | H2O |
TLQP-21, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor 1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8 μM). TLQP-21 activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions[1][2]. In Vitro: TLQP-21 is a peptide of 21 amino acids. At a dose of 3 μM TLQP-21 induces up to ~69% of the corresponding contraction promoted by acetylcholine[1][2].
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