m-PEG8-Amine
CAS No. : 869718-81-0
| Size | Price | Stock |
|---|---|---|
| 250mg | $16 | In-stock |
| 1g | $46 | In-stock |
| 5g | $222 | In-stock |
| 10g | $443 | In-stock |
| 25g | $1106 | In-stock |
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| Cat. No. : | HY-W040236 |
| M.Wt: | 383.48 |
| Formula: | C17H37NO8 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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