Gosogliptin (hydrochloride)
CAS No. : 869490-47-1
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| Cat. No. : | HY-10287A |
| M.Wt: | 439.33 |
| Formula: | C17H26Cl2F2N6O |
| Purity: | >98 % |
| Solubility: |
Gosogliptin hydrochloride is the hydrochloride of Gosogliptin (HY-10287). Gosogliptin (PF-00734200) is a potent, orally active, selective, and competitive inhibitor of DPP-IV, the enzyme mainly responsible for the degradation of the incretin peptides GLP-1 and glucose-dependent insulinotropic polypeptide. Gosogliptin demonstrates rapid and reversible inhibition of plasma DPP-4 activity. Gosogliptin stimulates insulin secretion and improves glucose tolerance[1][2].
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