CB-52


CAS No. : 869376-90-9

869376-90-9
Price and Availability of CAS No. : 869376-90-9
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Cat. No. : HY-121545
M.Wt: 417.62
Formula: C26H43NO3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 869376-90-9 :

CB-52 is the ligand and neutral antagonist of CB2 cannabinoid receptor[1]. In Vitro:CB-52 inhibits Forskolin (HY-15371)-induced cAMP formation by N18TG2 cells (IC50: 450 nM) and hCB1-CHO cells (EC50: 2600 nM)[1].
In Vivo:CB-52 (1 and 5 mg/kg, i.p.) decreases pain threshold to thermal stimulation in rats, and blocks WIN55,212-2 (2.5 mg/kg, i.p.) caused anti-nociceptive effect[1].

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