Neurokinin A


CAS No. : 86933-74-6

(Synonyms: Substance K; Neurokinin α; Neuromedin L; NKA)

86933-74-6
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Cat. No. : HY-P0197
M.Wt: 1133.32
Formula: C50H80N14O14S
Purity: >98 %
Solubility: H2O : 100 mg/mL (ultrasonic)
Introduction of 86933-74-6 :

Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues[1]. IC50 & Target:NK-2 receptor[1] In Vitro: Neurokinin A (substance K) is a peptide neurotransmitter of the tachykinin family with potential as a major mediator in human airway and gastrointestinal tissues. Neurokinin A acts via the NK-2 receptor believed to be localized on smooth muscle cells and pharmacologically coupled to a GTP-binding protein. Neurokinin A is a member of a family of peptide neurotransmitters known as tachykinins. These peptides are associated with the central and peripheral nervous systems and display a wide tissue distribution. Tachykinins share the COOH-terminal structure Phe-X-Gly-Leu-Met-NH. The best known members of this family are Substance P and Neurokinin A or Substance K[1].

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