ABT-384


CAS No. : 868623-40-9

868623-40-9
Price and Availability of CAS No. : 868623-40-9
Size Price Stock
5mg $350 In-stock
10mg $580 In-stock
25mg $1100 In-stock
50mg $1700 In-stock
100mg $2600 In-stock
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Cat. No. : HY-111262
M.Wt: 493.56
Formula: C25H34F3N5O2
Purity: >98 %
Solubility: DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 868623-40-9 :

ABT-384 is a potent, selective 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor. ABT-384 exhibits high affinity (Ki 0.1-2.7 nM) against rodent, monkey, and human 11β-HSD1. ABT-384 blocks regeneration of active cortisol. ABT-384 can be used for the research of Alzheimer’s disease (AD)[1][2]. IC50 & Target: Ki: 0.1-2.7 nM (rodent, monkey, and human 11β-HSD1)[2]

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