NIAD-4
CAS No. : 868592-56-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $85 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $240 | In-stock |
| 50mg | $380 | In-stock |
| 100mg | $600 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-111263 |
| M.Wt: | 334.43 |
| Formula: | C18H10N2OS2 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;warming) |
NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM[1]. In Vitro:NIAD-4 binds to amyloid aggregates, hinders its internal rotation, increases its fluorescence quantum yield and fluorescence intensity, thereby making it an effective tool for detecting amyloid. NIAD-4 can cross the blood-brain barrier, and used for amyloid fibrils imaging in brains due to its charge neutrality and low molecular weight. NIAD-4 exhibits an excitation wavelength of 475 nM and an emission wavelength of 610 nM[2][3].
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