SID 7969543


CAS No. : 868224-64-0

868224-64-0
Price and Availability of CAS No. : 868224-64-0
Size Price Stock
5mg $110 In-stock
10mg $155 In-stock
25mg $310 In-stock
50mg $520 In-stock
100mg $830 In-stock
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Cat. No. : HY-107404
M.Wt: 452.46
Formula: C24H24N2O7
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 868224-64-0 :

SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily[1][2]. In Vitro: SID 7969543 shows IC50s of >33,333 nM for RORα, VP-16, respectively[1].
SID 7969543 is assayed for functional activity against HEK 293T cells co-transfected with a plasmid encoding full length SF-1 and a second vector allowing expression of the luciferase gene under control of five tandem repeats of the natural SF-1 response element (SFRE). SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 values of 30 ± 15 nM[1].

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