Amino-PEG4-alcohol
CAS No. : 86770-74-3
| Size | Price | Stock |
|---|---|---|
| 100mg | $5 | In-stock |
| 250mg | $6 | In-stock |
| 1g | $11 | In-stock |
| 5g | $49 | In-stock |
| 10g | $96 | In-stock |
| 25g | $228 | In-stock |
| 100g | $911 | In-stock |
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| 500 g | Get quote | |
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| Cat. No. : | HY-W008005 |
| M.Wt: | 193.24 |
| Formula: | C8H19NO4 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic);DMSO : ≥ 100 mg/mL |
Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].
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- Amino-PEG4-alcohol
- Cat. No.:
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