10-Nitrocamptothecin


CAS No. : 86639-62-5

86639-62-5
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Cat. No. : HY-N2062
M.Wt: 393.35
Formula: C20H15N3O6
Purity: >98 %
Solubility:
Introduction of 86639-62-5 :

10-Nitrocamptothecin is a topoisomerase I inhibitor with an IC50 of 0.64 μM. 10-Nitrocamptothecin interferes with the formation of cleavable complexes, thereby inhibiting the activity of Topoisomerase I. 10-Nitrocamptothecin is applicable for cancer research[1]. In Vitro:10-Nitrocamptothecin (Compound 5e) (30 min) inhibits purified calf thymus topoisomerase I by forming a cleavable complex, with an IC50 of 0.64 μM[1].

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