TC-E 5001


CAS No. : 865565-29-3

865565-29-3
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Cat. No. : HY-108516
M.Wt: 409.46
Formula: C20H19N5O3S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 865565-29-3 :

TC-E 5001 is an inhibitor of Wnt pathway that inhibits tankyrase 1/2 (TNKS1/2) via novel adenosine pocket binding, with Kds of 79 nM and 28 nM, respectively. TC-E 5001 also inhibits Axin2 and STF, with IC50s of 0.709 μM and 0.215 μM, respectively[1][2]. In Vitro: TC-E 5001 inhibits TNKS2, with an IC50 of 33 nM[1].

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