Benazepril
CAS No. : 86541-75-5
(Synonyms: CGS14824A (free base))
| Size | Price | Stock |
|---|---|---|
| 10mg | $50 | In-stock |
| 25mg | $100 | In-stock |
| 50mg | $160 | In-stock |
| 100mg | $256 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-B0093 |
| M.Wt: | 424.49 |
| Formula: | C24H28N2O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Benazepril (CGS14824A free base) is an orally active angiotensin-converting enzyme (ACE) inhibitor to reduce angiotensin-II production. Benazepril inhibits oxidative stress and inhibits apoptosis by the PI3K/Akt signaling pathway. Benazepril improves diabetic nephropathy and decreases proteinuria. Benazepril can be used in the study of hypertension, heart failure and diabetic nephropathy[1][2]. In Vitro:Benazepril (1 μM; 1 h) alleviates oxidative stress and inhibits cell apoptosis through PI3K/Akt signaling pathway in Adriamycin (HY-15142A) treated H9c2 cells[1]. In Vivo:Benazepril (10 mg/kg; oral gavage; 16 weeks) has an improved effect in diabetic nephropathy rat model[2].
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