Islatravir (Standard)


CAS No. : 865363-93-5

(Synonyms: MK-8591 (Standard))

865363-93-5
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Cat. No. : HY-104012R
M.Wt: 293.25
Formula: C12H12FN5O3
Purity: >98 %
Solubility:
Introduction of 865363-93-5 :

Islatravir (Standard) is the analytical standard of Islatravir (HY-104012). This product is intended for research and analytical applications. Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Islatravir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. IC50 & Target:EC50: 0.068 nM (HIV-1 (WT)), 0.15 nM (HIV-1 (MDR)), 3.1 nM (HIV-1 (M184V))[1]

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