HAEGTFTSDVS
CAS No. : 864915-61-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
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| Cat. No. : | HY-P1224 |
| M.Wt: | 1150.15 |
| Formula: | C48H71N13O20 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide. In Vitro: The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists[2].
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