Auxinole
CAS No. : 86445-22-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $140 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $550 | In-stock |
| 100mg | $950 | In-stock |
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| Cat. No. : | HY-111444 |
| M.Wt: | 321.37 |
| Formula: | C20H19NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL;Ethanol : 2.5 mg/mL (ultrasonic;warming;heat to 60°C) |
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression. IC50 & Target: TIR1/AFB receptor[1] In Vitro: Auxinole is a potent auxin antagonist of TIR1/AFB receptors, and binds TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and then inhibits auxin-responsive gene expression. In addition, Auxinole competitively inhibits various auxin responses in planta[1]. Auxinole causes reduction in IAA-triggered depolarization in root hair cells. Auxinole (20 µM) also represses the transient increase in [Ca2+]cyt completely, and blocks Ca2+ response[2].
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