| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $250 | In-stock |
| 25mg | $500 | In-stock |
| 50mg | $800 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-106783 |
| M.Wt: | 963.13 |
| Formula: | C43H74N14O11 |
| Purity: | >98 % |
| Solubility: | DMSO : 16.67 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL |
Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[1][2][3].
In Vitro:Polymyxin B nonapeptide (2-32 μg/mL, 24 h) has a synergistic effect with Azithromycin (HY-17506)[1].
Polymyxin B nonapeptide (10 μg/mL) inhibits lipopolysaccharide (HY-D1056)-induced neutrophilic activation in a concentration-dependent manner[2].
In Vivo:Polymyxin B nonapeptide (1.5, 3.0 mg/kg intravenously for 29 days) does not exhibit neuromuscular blocking, neurotoxic, or nephrotoxic effects in rats as observed with polymyxin B sulfate[2].
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