McMMAF
CAS No. : 863971-19-1
(Synonyms: Maleimidocaproyl monomethylauristatin F)
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $250 | In-stock |
| 25mg | $550 | In-stock |
| 50mg | $770 | In-stock |
| 100mg | $1000 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-15578 |
| M.Wt: | 925.16 |
| Formula: | C49H76N6O11 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
McMMAF (Maleimidocaproyl monomethylauristatin F) is an active molecule linker for ADC, made by coupling the powerful microtubule inhibitor Monomethyl auristatin F (MMAF) (HY-15579) with the protecting group maleimidocaproyl. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth[1][2][3][4]. In Vitro:ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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