5-Hydroxy Propafenone (hydrochloride)
CAS No. : 86383-32-6
(Synonyms: GPV-129 (hydrochloride))
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| Cat. No. : | HY-12773A |
| M.Wt: | 393.90 |
| Formula: | C21H28ClNO4 |
| Purity: | >98 % |
| Solubility: |
5-Hydroxy Propafenone (hydrochloride) is an inhibitor of cardiac myocyte repolarizing currents. 5-Hydroxy Propafenone is an active metabolite of propafenone. 5-Hydroxy Propafenone (hydrochloride) inhibits transient outward potassium current (Ito) in isolated human arterial myocytes with an IC50 of 1.5 μM. 5-Hydroxy Propafenone (hydrochloride) is potent Ito inhibitor in neonatal rat ventricular myocytes[1].
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