MCHR1 antagonist 2


CAS No. : 863115-70-2

863115-70-2
Price and Availability of CAS No. : 863115-70-2
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5mg $130 In-stock
10mg $220 In-stock
25mg $470 In-stock
50mg $750 In-stock
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Cat. No. : HY-100321
M.Wt: 424.42
Formula: C23H21FN2O5
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic;adjust pH to 6 with HCl)
Introduction of 863115-70-2 :

MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM; MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells[1]. IC50 & Target: IC50: 65 nM (melanin concentrating hormone receptor 1), 4.0 nM (hERG in IMR-32 cells)[1] In Vitro: MCHR1 antagonist 2 (Compound 30) is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM. MCHR1 antagonist 2 has inhibitory effects on Ca2+ flux, and hERG, with IC50s of 196 ± 30 nM and 4.0 ± 0.8 nM, respectively, in IMR-32 cells[1].

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