α-Amyrin acetate
CAS No. : 863-76-3
| Size | Price | Stock |
|---|---|---|
| 1mg | $150 | In-stock |
| 5mg | $320 | In-stock |
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| 50 mg | Get quote | |
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| Cat. No. : | HY-N2842 |
| M.Wt: | 468.75 |
| Formula: | C32H52O2 |
| Purity: | >98 % |
| Solubility: | Ethanol : 1 mg/mL (ultrasonic;warming;heat to 60°C) |
α-Amyrin acetate is a pentacyclic triterpenoid compound with oral activity. α-Amyrin acetate can inhibit cancer cells proliferation and induce apoptosis. α-Amyrin acetate can reduce blood glucose level. α-Amyrin acetate can be used for the researches of cancer and metabolic disease, such as breast cancer and diabetes[1][2].
In Vitro:α-Amyrin acetate (2.5-10 μg/mL, 0-72 h) inhibits proliferation and colony formation in MDA-MB-231 cells[2].
α-Amyrin acetate (5-10 μg/mL, 24 h) induces apoptosis and increases caspase-3 activity in MDA-MB-231 cells[2].
α-Amyrin acetate (10 μg/mL, 24 h) promotes the cleavage of Poly polymerase, increased E-cadherin, and inhibits vimentin and phosphorylated extracellular signal-regulated activation in MDA-MB-231 cells[2].
In Vivo:α-Amyrin acetate (50 mg/kg, p.o., daily for 1-10 days) reduces the blood glucose level in diabetic rats[1].
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