Gastrazole


CAS No. : 862583-15-1

(Synonyms: JB95008)

862583-15-1
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Cat. No. : HY-19445
M.Wt: 687.63
Formula: C34H32FN5Na2O7
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 862583-15-1 :

Gastrazole (JB95008) is potent and selective CCK2/gastrin receptor antagonist. Gastrazole can decrease the level of gastric acid. Gastrazole inhibits the Gastrin-stimulated growth of pancreatic cancer[1][2]. IC50 & Target: CCK2/gastrin receptor[1] In Vivo: Gastrazole (0.15-3 μmol/kg; i.v.) dose-dependently inhibits the Pentagastrin-stimulated gastric acid secretion[2].

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