PF-610355
CAS No. : 862541-45-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $1235 | Get quote |
| 5mg | $2665 | Get quote |
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| Cat. No. : | HY-14296 |
| M.Wt: | 617.75 |
| Formula: | C34H39N3O6S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
PF-610355 is a long-acting inhaled β2-adrenoreceptor agonist, with an EC50 of 0.26 nM. PF-610355 has the potential for the study of asthma and COPD[1]. In Vivo: PF-610355 is a long-acting (once daily) inhaled β2-adrenoreceptor agonist. PF-610355 has low oral bioavailability due to poor absorption through the gut lumen and high first pass metabolism and warranted further progression. PF-610355 has a short half-life (Clint = 33 (μL/min)/mg) that suggested an unbound intrinsic clearance of >10000 (mL/min)/kg. PF-610355 exhibits an ideal pharmacokinetic profile for an inhaled agent[1].
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