Eicosapentaenoic acid ethyl ester
CAS No. : 86227-47-6
(Synonyms: EPA ethyl ester; Ethyl eicosapentaenoate; AMR101)
| Size | Price | Stock |
|---|---|---|
| 50mg | $72 | In-stock |
| 100mg | $120 | In-stock |
| 500mg | $420 | In-stock |
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| Cat. No. : | HY-B0747 |
| M.Wt: | 330.50 |
| Formula: | C22H34O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);Ethanol : 50 mg/mL (ultrasonic) |
Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats[1][2][3].
In Vivo: Eicosapentaenoic acid ethyl ester (300 mg/kg, oral, For 4 weeks) can inhibit the decrease of thyroid hormone levels and the change of thyroid follicles induced by 1-methyl-2-imidazole thiol (MMI) in hypothyroidism rats[2].
Eicosapentaenoic acid ethyl ester (1 g/kg, gavage for 5 weeks) reverses the increase in plasma cholesterol level and decreased circulating triglyceride level in rats with high-fat diet[3].
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