IM-54
CAS No. : 861891-50-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $130 | In-stock |
| 10mg | $204 | In-stock |
| 25mg | $367 | In-stock |
| 50mg | $514 | In-stock |
| 100mg | $720 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-108351 |
| M.Wt: | 325.40 |
| Formula: | C19H23N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death[1][2].
In Vitro: IM-54 selectively inhibits oxidative stress-induced necrosis, but it does not inhibit apoptosis induced by various anticancer drugs or Fas ligand, or necroptosis[1].
IM-54 shows strong inhibition of H2O2-induced necrosis, with an IC50 of 0.25 μM in HL-60 cells[1].
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